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2C-B-FLY vs 5-MeO-DMT

A side-by-side research comparison of 2C-B-FLY and 5-MeO-DMT across mechanism, dosing, half-life, benefits, side effects and research status.

Comparison table

Attribute2C-B-FLY5-MeO-DMT
Full name8-Bromo-2,3,6,7-benzodifuranyl-isopropylamine5-Methoxy-N,N-dimethyltryptamine
CategoryPsychedelicsPsychedelics
StatusSchedule I (research compound)Schedule I (research compound)
MechanismActivates serotonin 5-HT2A receptors.Strongly activates serotonin 5-HT1A and 5-HT2A receptors, producing rapid and intense changes in consciousness.
Molecular weight296.16 g/mol218.30 g/mol
Half-lifeModerateShort (minutes)
BioavailabilityOralInhaled/injected
Typical doseVaries by individual and settingLow milligram range in clinical studies
FrequencyOccasionalOne to a few supervised sessions
RouteOralInhalation or injection in research settings

2C-B-FLY reported benefits

  • Warm, sensual experience
  • Longer than 2C-B
  • Phenethylamine research compound
  • Distinct "FLY" structure

5-MeO-DMT reported benefits

  • Studied for treatment-resistant depression
  • Short duration suits clinical use
  • Explored for anxiety
  • Rapid onset of effects

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Research and educational reference only. Not medical advice.