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Myostatin Inhibitor vs RAD-140 (Testolone)

A side-by-side research comparison of Myostatin Inhibitor and RAD-140 (Testolone) across mechanism, dosing, half-life, benefits, side effects and research status.

Comparison table

AttributeMyostatin InhibitorRAD-140 (Testolone)
Full nameMyostatin Inhibitor Peptides (Anti-GDF-8)Testolone (RAD-140)
CategoryMuscle GrowthMuscle Growth
StatusResearch compoundInvestigational (not approved; banned in sport)
MechanismPropeptide mimics bind mature myostatin; peptide aptamers block ActRIIB; small antagonists compete for receptor. All prevent myostatin-mediated suppression of muscle growth.Acts as a strong, tissue-selective androgen receptor agonist in muscle and bone, driving anabolic signaling with a higher anabolic-to-androgenic ratio than testosterone in preclinical models.
Molecular weight2,000-15,000 Da (varies)393.83 Da
Half-life4-48 hours (design-dependent)~16-20 hours
BioavailabilityVariable (SubQ)Oral
Typical dose50-500 mcgCommonly cited 5-15 mg/day (research)
Frequency3-7x per weekOnce daily
RouteSubcutaneousOral

Myostatin Inhibitor reported benefits

  • Muscle growth promotion
  • Strength increase
  • Myostatin blockade
  • Muscle wasting treatment potential
  • Metabolic improvement

RAD-140 (Testolone) reported benefits

  • Strong lean muscle gains (research)
  • Increased strength
  • Studied originally for muscle wasting and breast cancer
  • Bone-supportive signaling

Related comparisons

Research and educational reference only. Not medical advice.