Cerebrolysin (Cerebrolysin (Brain-Derived Peptide Preparation))
A multi-peptide preparation from porcine brain containing neurotrophic factors. Approved in 40+ countries for stroke and dementia, providing a cocktail of low-MW neuropeptides.
How it works
Contains fragments mimicking NGF, BDNF, GDNF, CNTF. Enhances synaptic plasticity, promotes neuronal sprouting, reduces amyloid-beta, and stabilizes calcium homeostasis.
Key facts
- Molecular weight: <10,000 Da (peptide fraction)
- Half-life: 4-6 hours
- Bioavailability: High (IM/IV)
- Storage: Refrigerated 2-8°C. Amber ampoules.
Dosing overview
- Typical dose: 5-30 mL
- Frequency: Daily for 10-20 days
- Duration: 10-20 day courses, 2-4x yearly
- Route: Intramuscular or IV
Reported benefits
- Neurotrophic support
- Stroke recovery
- Memory improvement
- Neuroprotection
- Synaptic plasticity
- Approved in 40+ countries
Possible side effects
- Injection pain
- Dizziness
- Headache
- Agitation
- Allergic reaction (porcine)
Research
- Cerebrolysin in acute ischemic stroke (CASTA) (2020): 30mL daily for 10 days improved neurological recovery at 90 days in moderate-severe stroke.
- Cerebrolysin in Alzheimer disease (2021): Six-month courses stabilized ADAS-Cog scores vs progressive decline in placebo over 28 weeks.
Compare Cerebrolysin
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Research and educational reference only. Not medical advice.