NA-Selank (N-Acetyl Selank (Acetylated Selank))
An acetylated form of Selank with improved stability and enhanced bioavailability. Same anxiolytic and cognitive benefits with longer duration.
How it works
Same tuftsin-derived mechanism as Selank with acetyl group providing protease resistance; modulates GABA, enhances BDNF.
Key facts
- Molecular weight: 793.91 Da
- Half-life: ~5-10 minutes (effective 4-6 hours)
- Bioavailability: ~95% intranasal
- Storage: Refrigerated 2-8°C.
Dosing overview
- Typical dose: 200-400 mcg
- Frequency: 1-2x daily
- Duration: 2-4 weeks
- Route: Intranasal spray
Protocol notes
- Typical use is 1-2 nasal sprays delivering ~200-400 mcg total per dose, once or twice daily.
- Many use it situationally for acute anxiety/focus rather than around the clock.
- The acetylated form lasts longer than regular Selank, so fewer daily doses are usually needed.
Reported benefits
- Enhanced anxiolytic effect
- Improved stability
- Better bioavailability
- Cognitive focus
- Stress resilience
Possible side effects
- Nasal irritation
- Mild sedation (rare)
- Headache
Research
- N-Acetyl peptide modifications (2019): Acetylation extended effective half-life by 3-4x and improved BBB penetration.
- Modified tuftsin analogs for anxiety (2020): NA-Selank showed 40% greater anxiolytic potency than Selank.
Compare NA-Selank
Community discussions about NA-Selank
- Anyone switched from Selank to NA-Selank for longer effects? - 0 comments
- Looking at NA-Selank amidate – any thoughts on the latest data? - 4 comments
- NA-Selank + NA-Semax stack for focus – timing advice? - 5 comments
- Nootropic God Stack sounds insane, anyone actually run all four at once? - 7 comments
- NA-Selank nasal irritation tips after 2 weeks of daily use - 4 comments
- Ask the community about NA-Selank
Research and educational reference only. Not medical advice.