AHK-Cu vs PTD-DBM
A side-by-side research comparison of AHK-Cu and PTD-DBM across mechanism, dosing, half-life, benefits, side effects and research status.
Comparison table
| Attribute | AHK-Cu | PTD-DBM |
|---|---|---|
| Full name | AHK-Cu (Alanine-Histidine-Lysine Copper Peptide) | PTD-DBM (Wnt Pathway Hair Peptide) |
| Category | Hair Growth | Hair Growth |
| Status | Cosmetic research peptide | Research peptide (topical) |
| Mechanism | Delivers copper to tissue and signals angiogenesis and growth-factor activity (notably VEGF) around hair follicles, promoting follicle vascularization, prolonging the anagen (growth) phase, and supporting collagen production. | PTD-DBM disrupts the interaction between CXXC5 and Dishevelled, releasing a natural brake on the Wnt/beta-catenin signaling pathway. Enhanced Wnt signaling promotes hair follicle neogenesis and regeneration. |
| Molecular weight | ~403 Da (with copper) | ~ (short cell-penetrating peptide) |
| Half-life | Topical (local action) | Topical (local action) |
| Bioavailability | Topical (serum/solution); local delivery | Topical (local delivery) |
| Typical dose | ~0.5-2 mg/mL topical serum | Topical scalp application (research) |
| Frequency | 1-2x daily on scalp | Daily |
| Route | Topical | Topical |
AHK-Cu reported benefits
- Hair follicle support and growth signaling
- Follicle vascularization (VEGF)
- Prolongs anagen growth phase
- Collagen and skin support
- Antioxidant copper delivery
PTD-DBM reported benefits
- Activates Wnt/beta-catenin hair pathway
- Promotes follicle neogenesis (research)
- Synergy with valproic acid
- Non-hormonal hair mechanism
Related comparisons
Research and educational reference only. Not medical advice.