Livagen vs NAC
A side-by-side research comparison of Livagen and NAC across mechanism, dosing, half-life, benefits, side effects and research status.
Comparison table
| Attribute | Livagen | NAC |
|---|---|---|
| Full name | Livagen (Lys-Glu-Asp-Ala Liver/Lymphocyte Bioregulator) | N-Acetyl Cysteine |
| Category | Detox & Antioxidant | Detox & Antioxidant |
| Status | Research compound (peptide bioregulator) | Dietary supplement / FDA-approved (Mucomyst) |
| Mechanism | As a signal peptide (Lys-Glu-Asp-Ala), it is proposed to decondense chromatin (heterochromatin) in lymphocytes and regulate gene expression in hepatic tissue, supporting liver function and cellular activity. | Provides cysteine for glutathione synthesis (rate-limiting step). Directly scavenges free radicals via sulfhydryl group. Chelates mercury, lead, and arsenic. Modulates glutamate via system Xc- transporter for neuropsychiatric effects. |
| Molecular weight | ~460 Da | 163.19 Da |
| Half-life | Short (peptide) | ~5.6 hours |
| Bioavailability | Oral (encapsulated) or subcutaneous | ~6-10% oral (poor but effective due to GSH replenishment) |
| Typical dose | ~1-2 capsules/day or short injectable courses | 600-1800 mg |
| Frequency | Once daily | 1-2x daily |
| Route | Oral capsule or subcutaneous | Oral capsule or IV (hospital) |
Livagen reported benefits
- Liver function support
- Lymphocyte chromatin activation (proposed)
- Detox/antioxidant support
- Short course-based protocol
NAC reported benefits
- Glutathione replenishment
- Liver protection (acetaminophen, alcohol)
- Heavy metal chelation
- Mucus thinning (respiratory)
- OCD/addiction support
- Anti-inflammatory
Related comparisons
Research and educational reference only. Not medical advice.