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BPC-157 (Body Protection Compound-157)

Category: Healing & Recovery. Status: Research compound.

A pentadecapeptide derived from human gastric juice that promotes wound healing and tissue repair. Demonstrates remarkable regenerative properties across multiple tissue types including tendon, muscle, and nervous system.

How it works

Upregulates growth factor expression including VEGF and promotes angiogenesis, modulates nitric oxide system, and interacts with the dopaminergic system.

Key facts

  • Molecular weight: 1419.53 Da
  • Half-life: ~4 hours
  • Bioavailability: Variable; oral and injectable forms available
  • Storage: Lyophilized: room temperature. Reconstituted: 2-8°C for up to 30 days.

Dosing overview

  • Typical dose: 250-500 mcg per dose
  • Frequency: 1-2x daily
  • Duration: 4-12 weeks
  • Route: Subcutaneous injection (or oral capsules)

Protocol notes

  • Most run 250-500 mcg once or twice daily, splitting AM/PM doses.
  • For a local injury, inject subcutaneously as close to the injury site as practical.
  • Systemic/gut issues are typically dosed oral or away from the site; healing protocols often run 2-4 weeks then reassess.
  • Many cycle 4-6 weeks on, then a break once the target tissue has recovered.

Reported benefits

  • Accelerated tendon and ligament healing
  • Gut lining protection and repair
  • Neuroprotective effects
  • Anti-inflammatory properties
  • Muscle tear recovery

Possible side effects

  • Mild nausea (oral)
  • Injection site irritation
  • Dizziness (rare)
  • Fatigue (rare)

Research

  • BPC 157 and its role in accelerating wound healing (2021): Demonstrated significant acceleration of cutaneous wound healing in rat models with enhanced angiogenesis.
  • Stable gastric pentadecapeptide BPC 157 in tendon healing (2019): Showed improved biomechanical properties of healing tendons compared to controls.

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Research and educational reference only. Not medical advice.