GHRP-6 (Growth Hormone Releasing Peptide-6)
One of the original synthetic GH releasing peptides. Strongly stimulates appetite through ghrelin pathways while promoting robust GH release.
How it works
Activates GHSR-1a on pituitary for GH release and hypothalamic neurons for appetite. Triggers gastric motility and ghrelin-like reward signaling.
Key facts
- Molecular weight: 873 Da
- Half-life: 2-3 hours
- Bioavailability: High (SubQ)
- Storage: Lyophilized: -20°C. Reconstituted: 2-8°C for 21 days.
Dosing overview
- Typical dose: 100-300 mcg
- Frequency: 2-3x daily
- Duration: 8-12 weeks
- Route: Subcutaneous
Reported benefits
- Strong GH release
- Powerful appetite stimulation
- Gastric motility improvement
- Recovery enhancement
- Gut healing support
Possible side effects
- Intense hunger
- Cortisol elevation
- Prolactin increase
- Water retention
- Light-headedness
Research
- GHRP-6 cytoprotective effects on gastric mucosa (2020): Demonstrated gastroprotective effects through NO pathways, reducing ulcer index by 65%.
- GHRP-6 in catabolic states (2019): Reversed nitrogen wasting and improved lean mass by 4.2kg over 8 weeks in catabolic patients.
Compare GHRP-6
Community discussions about GHRP-6
- GHRP-6 appetite vs Ipamorelin for night time use - 4 comments
- Ipamorelin vs GHRP-6 for hunger management and sleep - 0 comments
- Confused about starting with ghrp-6 and ghrh blends - 0 comments
- Testing the Superman stack vs just CJC and Ipamorelin - 4 comments
- GHRP-6 appetite issues vs GH release - 4 comments
- Ask the community about GHRP-6
Research and educational reference only. Not medical advice.