Psilocin (4-Hydroxy-DMT (active form of psilocybin))
The active compound that psilocybin turns into in the body. It is what actually produces the effects of magic mushrooms, and is studied for the same depression and anxiety uses as psilocybin.
How it works
Directly activates serotonin 5-HT2A receptors. Psilocybin is a "prodrug" that the body converts into psilocin.
Key facts
- Molecular weight: 204.27 g/mol
- Half-life: ~1-3 hours
- Bioavailability: Oral
- Storage: Research/reference only.
Dosing overview
- Typical dose: Varies by individual and setting
- Frequency: Occasional
- Duration: Acute effects last 3-6 hours
- Route: Oral
Protocol notes
- Behaves like psilocybin since psilocybin turns into psilocin in the body; taken orally and felt within 20-40 minutes.
- Used in the same lie-down, eyeshades-and-music format as psilocybin in research.
- Rarely handled on its own outside labs because it is less stable than psilocybin.
Reported benefits
- The active form behind psilocybin
- Studied for depression and anxiety
- Faster onset than psilocybin
- Classic serotonergic psychedelic
Possible side effects
- Anxiety or fear
- Nausea
- Raised heart rate and blood pressure
- Temporary confusion
Compare Psilocin
Community discussions about Psilocin
- how to reconstitute 4-aco-dmt for first try? - 6 comments
- Spike in Blood Pressure After My First Psilocybin Session - 4 comments
- 4-aco-dmt: a more stable psilocybin pro‑drug catching attention - 3 comments
- Ask the community about Psilocin
Research and educational reference only. Not medical advice.