Thymosin Beta-4 (Thymosin Beta-4 (Full Length))
A 43-amino acid peptide that is the primary G-actin sequestering molecule in mammalian cells. Plays a critical role in tissue repair, regeneration, and protection after injury.
How it works
Sequesters G-actin to regulate cytoskeleton dynamics, promotes stem cell differentiation, and activates anti-inflammatory and anti-apoptotic pathways.
Key facts
- Molecular weight: 4921 Da
- Half-life: ~6-8 hours
- Bioavailability: ~95% subcutaneous
- Storage: Lyophilized: -20°C. Reconstituted: 2-8°C for up to 14 days.
Dosing overview
- Typical dose: 1-5 mg
- Frequency: 2-3x per week
- Duration: 4-12 weeks
- Route: Subcutaneous injection
Protocol notes
- Loading phase: commonly ~2-5 mg split across 2-3 subcutaneous injections per week for the first 4-6 weeks.
- Maintenance phase: a single 2-5 mg dose once weekly (or every other week) to hold results.
- Frequently stacked with BPC-157 for soft-tissue and systemic recovery.
Reported benefits
- Comprehensive tissue repair
- Cardiac regeneration
- Neurological recovery
- Corneal healing
- Anti-fibrotic effects
Possible side effects
- Injection site swelling
- Temporary fatigue
- Mild headache
Research
- Thymosin beta-4 in cardiac repair (2020): Promoted cardiomyocyte survival and neovascularization post-ischemic injury.
- Corneal wound healing with Tβ4 (2018): Accelerated corneal re-epithelialization and reduced scarring in clinical evaluation.
Compare Thymosin Beta-4
Community discussions about Thymosin Beta-4
- MDPI review on TB-500 and tissue repair - 4 comments
- TB-500 for injury recovery, what the research actually shows - 4 comments
- TB-500 and TA1 stack for overtraining recovery? - 4 comments
- Ask the community about Thymosin Beta-4
Research and educational reference only. Not medical advice.