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Ayahuasca vs ETH-LAD

A side-by-side research comparison of Ayahuasca and ETH-LAD across mechanism, dosing, half-life, benefits, side effects and research status.

Comparison table

AttributeAyahuascaETH-LAD
Full nameAyahuasca (DMT + MAO inhibitor brew)6-Ethyl-6-nor-LSD
CategoryPsychedelicsPsychedelics
StatusTraditional/ceremonial; research compoundSchedule I (research compound)
MechanismThe MAO-inhibiting vine (harmine and related compounds) stops the body from breaking down DMT, allowing an oral psychedelic experience that activates serotonin 5-HT2A receptors.Activates serotonin 5-HT2A receptors with high potency.
Molecular weightMixture (no single value)337.46 g/mol
Half-lifeSeveral hours (extended by MAO inhibition)~3-5 hours
BioavailabilityOralOral
Typical doseBrew-based, varies by preparationVaries by individual and setting
FrequencyCeremonial or occasional study sessionsOccasional
RouteOral brewOral

Ayahuasca reported benefits

  • Studied for treatment-resistant depression
  • Explored for grief and trauma
  • Long history of ceremonial use
  • May produce lasting shifts in outlook

ETH-LAD reported benefits

  • Highly visual
  • More potent than LSD by weight
  • Lysergamide research compound
  • Long experience

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Research and educational reference only. Not medical advice.