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Serrapeptase vs Vesugen

A side-by-side research comparison of Serrapeptase and Vesugen across mechanism, dosing, half-life, benefits, side effects and research status.

Comparison table

AttributeSerrapeptaseVesugen
Full nameSerrapeptase (Serratiopeptidase)Vesugen (Lys-Glu-Asp Vascular Bioregulator)
CategoryCardiovascularCardiovascular
StatusDietary supplementResearch compound (peptide bioregulator)
MechanismDegrades non-living tissue including fibrin, blood clots, mucus, and arterial plaque without harming living cells. Inhibits bradykinin release and reduces prostaglandin synthesis for anti-inflammatory effects.As a signal peptide (Lys-Glu-Asp), it is proposed to enter cells and regulate gene expression in vascular tissue, supporting endothelial function, vascular tone, and normal vessel-wall maintenance.
Molecular weight~52,000 Da~390 Da
Half-life~4-6 hoursShort (peptide)
BioavailabilityOral (enteric-coated required); detectable in bloodstreamOral (encapsulated) or subcutaneous
Typical dose120,000-240,000 SPU~1-2 capsules/day or short injectable courses
FrequencyDaily on empty stomachOnce daily
RouteOral (enteric-coated)Oral capsule or subcutaneous

Serrapeptase reported benefits

  • Reduced inflammation and swelling
  • Arterial plaque modulation
  • Mucus/biofilm breakdown
  • Post-surgical recovery
  • Sinus/respiratory clearing
  • Pain reduction

Vesugen reported benefits

  • Vascular/endothelial support
  • Proposed vascular tissue regulation
  • Short course-based protocol
  • Part of bioregulator longevity systems

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Research and educational reference only. Not medical advice.