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Vesugen (Vesugen (Lys-Glu-Asp Vascular Bioregulator))

Category: Cardiovascular. Status: Research compound (peptide bioregulator).

A short synthetic tripeptide bioregulator from the Khavinson family, targeted at vascular tissue. It is used within the peptide-bioregulator community for vascular health and endothelial support, typically in short repeated courses.

How it works

As a signal peptide (Lys-Glu-Asp), it is proposed to enter cells and regulate gene expression in vascular tissue, supporting endothelial function, vascular tone, and normal vessel-wall maintenance.

Key facts

  • Molecular weight: ~390 Da
  • Half-life: Short (peptide)
  • Bioavailability: Oral (encapsulated) or subcutaneous
  • Storage: Room temperature (capsules) or refrigerate (injectable).

Dosing overview

  • Typical dose: ~1-2 capsules/day or short injectable courses
  • Frequency: Once daily
  • Duration: 10-30 day courses
  • Route: Oral capsule or subcutaneous

Protocol notes

  • Bioregulators are usually taken as short courses (often 10-30 days), repeated a few times per year.
  • Oral encapsulated forms are taken once daily on an empty stomach.
  • Injectable courses follow a similar short-course, repeatable pattern.

Reported benefits

  • Vascular/endothelial support
  • Proposed vascular tissue regulation
  • Short course-based protocol
  • Part of bioregulator longevity systems

Possible side effects

  • Limited Western clinical data
  • Injection site reactions (injectable)
  • Unknown long-term effects

Research

  • Peptide bioregulators and vascular tissue (2018): Short peptide bioregulators were reported to influence gene expression and tissue-specific function in Russian research programs.

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Research and educational reference only. Not medical advice.