AHK-Cu Research Guide

Full name: AHK-Cu (Alanine-Histidine-Lysine Copper Peptide)

A copper-binding tripeptide (Ala-His-Lys) chelated to copper, closely related to GHK-Cu but especially popular for hair growth and follicle support. Widely used topically in biohacker hair and scalp formulations.

How AHK-Cu Works

Delivers copper to tissue and signals angiogenesis and growth-factor activity (notably VEGF) around hair follicles, promoting follicle vascularization, prolonging the anagen (growth) phase, and supporting collagen production.

Dosing Protocol

• Typical dose: ~0.5-2 mg/mL topical serum
• Frequency: 1-2x daily on scalp
• Duration: Ongoing
• Route: Topical

Reported Benefits

• Hair follicle support and growth signaling
• Follicle vascularization (VEGF)
• Prolongs anagen growth phase
• Collagen and skin support
• Antioxidant copper delivery

Potential Side Effects

• Scalp irritation (rare)
• Temporary blue-green staining
• Contact sensitivity (rare)

Research Citations

1. AHK-Cu and hair follicle growth (2007) - Copper tripeptide AHK-Cu increased hair follicle size and promoted VEGF-driven follicle vascularization in studies.
2. Copper peptides and dermal support (2015) - Copper-binding peptides supported angiogenesis, collagen synthesis, and skin/scalp remodeling.

Related Hair Growth Compounds

• Dutasteride - Full Profile
• Finasteride - Full Profile
• RU-58841 - Full Profile
• Minoxidil - Full Profile
• GHK-Cu Topical - Full Profile
• TB-4 Topical (Hair) - Full Profile

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