Superman Stack (Superman (CJC-1295 + Ipamorelin + MK-677))
The premier growth hormone optimization stack combining the three most effective GH-releasing compounds. CJC-1295 provides sustained GHRH stimulation, Ipamorelin gives clean pulsatile GH release, and MK-677 maintains elevated GH/IGF-1 levels around the clock.
How it works
CJC-1295 (no DAC) mimics GHRH for pituitary stimulation. Ipamorelin acts as a selective ghrelin receptor agonist for GH release without cortisol/prolactin. MK-677 provides oral, long-acting ghrelin mimetic action for sustained IGF-1 elevation.
Key facts
- Molecular weight: Multiple compounds
- Half-life: CJC: ~30min, Ipamorelin: ~2h, MK-677: ~24h
- Bioavailability: CJC/Ipa: ~95% SC, MK-677: ~60% oral
- Storage: CJC/Ipa lyophilized: -20°C. MK-677: room temperature.
Dosing overview
- Typical dose: CJC-1295 100mcg + Ipamorelin 200mcg + MK-677 25mg oral
- Frequency: CJC/Ipa: nightly, MK-677: daily
- Duration: 12-16 weeks
- Route: Subcutaneous + Oral
Protocol notes
- CJC-1295 (no DAC) 100 mcg + Ipamorelin 200 mcg combined in one subcutaneous shot before bed (empty stomach).
- MK-677 25 mg taken orally once daily - many take it in the evening to support sleep and GH pulse.
- Inject the CJC/Ipa on an empty stomach (no food ~2 h before/30 min after) so a carb/fat spike doesn't blunt the GH pulse.
- Run for 12-16 weeks, then take a break to keep the pituitary responsive.
Reported benefits
- Maximized GH output
- 24/7 GH/IGF-1 elevation
- Improved sleep quality
- Enhanced fat loss
- Increased muscle recovery
- Anti-aging effects
Possible side effects
- Increased hunger (MK-677)
- Water retention
- Numbness/tingling in hands
- Elevated fasting glucose
- Vivid dreams
Research
- Combination GHRH/GHRP therapy outcomes (2021): Triple therapy produced 3.2x GH pulse amplitude vs CJC-1295 alone with improved body composition.
- MK-677 combined with injectable GH secretagogues (2020): Addition of MK-677 to CJC/Ipa protocol maintained elevated IGF-1 throughout the day vs nighttime-only dosing.
Compare Superman Stack
Community discussions about Superman Stack
- Question about CJC and Ipamorelin timing for sleep vs hunger - 2 comments
- Testing the Superman stack vs just CJC and Ipamorelin - 4 comments
- Trying a low‑dose Superman + PE‑22‑28 combo for mood and recovery – need feedback - 6 comments
- Increased Hunger With MK-677 (Superman Stack): How Bad Did It Get For You? - 4 comments
- Is MK-677 overkill when using CJC and Ipamorelin? - 6 comments
- Ask the community about Superman Stack
Research and educational reference only. Not medical advice.