GDF-11 vs Taurine
A side-by-side research comparison of GDF-11 and Taurine across mechanism, dosing, half-life, benefits, side effects and research status.
Comparison table
| Attribute | GDF-11 | Taurine |
|---|---|---|
| Full name | Growth Differentiation Factor 11 | Taurine (2-Aminoethanesulfonic Acid) |
| Category | Anti-Aging | Anti-Aging |
| Status | Research compound | OTC supplement |
| Mechanism | Signals through activin type II receptors and SMAD2/3 to restore stem cell function, promote neurogenesis, and improve vascular remodeling in the context of aging. | Acts as a cytoprotective osmolyte and antioxidant, stabilizes mitochondrial function, modulates calcium signaling and GABA-A/glycine receptors, reduces inflammation, and supports bile acid conjugation. Taurine deficiency accelerates cellular senescence markers. |
| Molecular weight | 12,500 Da | 125.15 Da |
| Half-life | 6-8 hours | ~1 hour (plasma) |
| Bioavailability | Moderate (SubQ/IV) | ~90-100% oral |
| Typical dose | 0.1-0.5 mg/kg (research) | 1-6 g per day |
| Frequency | Daily (animal studies) | 1-3x daily |
| Route | Subcutaneous | Oral (powder or capsule) |
GDF-11 reported benefits
- Potential tissue rejuvenation
- Neurogenesis stimulation
- Cardiac hypertrophy reversal
- Muscle stem cell activation
- Vascular remodeling
Taurine reported benefits
- Supports mitochondrial function
- Cardiovascular and blood pressure support
- Exercise endurance
- Antioxidant and anti-inflammatory
- Longevity/healthspan signal
- Calming/GABAergic effects
Related comparisons
Research and educational reference only. Not medical advice.