DXM Research Guide

Full name: Dextromethorphan

A common cough-medicine ingredient that becomes a powerful dissociative psychedelic at high doses. Included for awareness because of how widely available it is.

How DXM Works

At high doses it blocks NMDA glutamate receptors, producing dissociation similar to ketamine.

Dosing Protocol

• Typical dose: Varies by individual and setting
• Frequency: Occasional
• Duration: Acute effects last 4-8 hours
• Route: Oral

Reported Benefits

• Widely studied cough medicine
• Dissociative effects at high doses
• Included for awareness
• Researched for mood (as a combo drug)

Potential Side Effects

• Nausea and vomiting
• Dangerous interactions with SSRIs (serotonin syndrome)
• Confusion and impaired coordination
• Liver risk from combo products

Related Psychedelics Compounds

• MDMA - Full Profile
• Psilocybin - Full Profile
• LSD - Full Profile
• Ibogaine - Full Profile
• DMT - Full Profile
• Ayahuasca - Full Profile

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