KPV Research Guide

Full name: Lysine-Proline-Valine Tripeptide

A tripeptide derived from alpha-MSH with potent anti-inflammatory properties. Shows promise for gut inflammation, skin conditions, and immune modulation without melanogenic effects.

How KPV Works

Inhibits NF-kB signaling pathway, reduces pro-inflammatory cytokine production (TNF-α, IL-6), and modulates immune cell activation.

Dosing Protocol

• Typical dose: 200-500 mcg per dose
• Frequency: 1-2x daily
• Duration: 4-8 weeks
• Route: Oral, topical, or subcutaneous

Reported Benefits

• Potent anti-inflammatory
• Gut inflammation reduction
• Skin condition improvement
• Immune modulation

Potential Side Effects

• Mild drowsiness
• Injection site reaction
• Transient flushing

Research Citations

1. KPV anti-inflammatory effects in colitis models (2021) - Significantly reduced colonic inflammation and improved histological scores in IBD animal models.
2. Alpha-MSH derived peptides in skin inflammation (2019) - Demonstrated reduction in inflammatory markers without melanotropic activity.

Related Healing & Recovery Compounds

• BPC-157 - Full Profile
• TB-500 - Full Profile
• Pentosan Polysulfate - Full Profile
• Thymosin Beta-4 - Full Profile
• LL-37 - Full Profile
• BPC-157 (Oral) - Full Profile

View full KPV profile with 3D molecule viewer →