Lactoferrin Research Guide

Full name: Lactoferrin (Iron-Binding Glycoprotein)

A multifunctional iron-binding glycoprotein found in milk and mucosal secretions with broad antimicrobial, anti-inflammatory, and immunomodulatory activities.

How Lactoferrin Works

Sequesters iron from pathogens (bacteriostatic), directly disrupts bacterial membranes, activates NK cells and macrophages, and modulates inflammatory cytokines.

Dosing Protocol

• Typical dose: 200-600 mg
• Frequency: 1-2x daily
• Duration: 4-12 weeks
• Route: Oral capsule or powder

Reported Benefits

• Broad antimicrobial activity
• Iron homeostasis regulation
• Gut immune support
• Anti-biofilm properties
• Prebiotic effects

Potential Side Effects

• Mild GI discomfort
• Constipation (iron-related)
• Rare allergic reaction (dairy)

Research Citations

1. Lactoferrin supplementation for immune health (2020) - Reduced incidence and duration of respiratory infections by 40% in elderly subjects over 3 months.
2. Lactoferrin gut-immune axis modulation (2021) - Enhanced secretory IgA production and improved gut barrier function in randomized controlled trial.

Related Immune Support Compounds

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