Research compounds for hair regrowth and follicle stimulation - GHK-Cu, PTD-DBM, thymosin beta-4 and topical peptide protocols.
A naturally occurring copper-binding tripeptide that declines with age. Promotes collagen synthesis, wound healing, and has broad regenerative effects on skin, hair follicles, and tissues.
Dose: 1-3 mg topical ยท 200-500 mcg injectable | Route: Topical cream/serum or subcutaneous injection
A cell-penetrating peptide researched for hair regeneration by activating the Wnt/beta-catenin pathway. It became popular in biohacker hair protocols after studies paired it with valproic acid to indu
Dose: Topical scalp application (research) | Route: Topical
A 43-amino acid peptide that is the primary G-actin sequestering molecule in mammalian cells. Plays a critical role in tissue repair, regeneration, and protection after injury.
Dose: 1-5 mg | Route: Subcutaneous injection
Read full Thymosin Beta-4 guide →
The first-line FDA-approved treatment for male pattern hair loss. Selectively inhibits type II 5-alpha reductase, reducing scalp DHT levels by ~60-70% to slow or reverse follicular miniaturization.
Dose: 1 mg (hair) or 5 mg (prostate) | Route: Oral tablet
A dual 5-alpha reductase inhibitor (type I and II) that blocks ~90% of DHT production, compared to finasteride's ~70%. Increasingly prescribed off-label for androgenetic alopecia when finasteride
Dose: 0.5 mg | Route: Oral capsule
A non-steroidal topical anti-androgen that blocks DHT at the hair follicle receptor without systemic hormonal effects. Applied directly to the scalp, it competes with DHT for androgen receptor binding
Dose: 50-100 mg in 1mL vehicle | Route: Topical (dissolved in ethanol/PG vehicle)
A potassium channel opener and vasodilator that stimulates hair growth independent of hormonal mechanisms. Works for both men and women with androgenetic alopecia. Available OTC in topical and increas
Dose: 5% topical (1mL 2x/day) or 2.5-5 mg oral | Route: Topical solution/foam or oral tablet
The copper-peptide complex applied topically to the scalp to stimulate hair follicle regeneration. GHK-Cu increases follicle size, promotes angiogenesis around follicles, and extends the anagen growth
Dose: 1-2 mg/mL in scalp solution or serum | Route: Topical scalp serum or mesotherapy injection
Read full GHK-Cu Topical guide →
Thymosin Beta-4 applied topically or via mesotherapy for hair follicle stem cell activation. TB-4 promotes migration of hair follicle stem cells from the bulge region into the follicular matrix, poten
Dose: 50-200 mcg per scalp application or 0.1% solution | Route: Topical serum or mesotherapy (intradermal injection)
Read full TB-4 Topical (Hair) guide →
A copper-binding tripeptide (Ala-His-Lys) chelated to copper, closely related to GHK-Cu but especially popular for hair growth and follicle support. Widely used topically in biohacker hair and scalp f
Dose: ~0.5-2 mg/mL topical serum | Route: Topical