Top anti-aging peptides backed by research - epitalon, GHK-Cu, thymosin alpha-1 and more for cellular rejuvenation.
A naturally occurring copper-binding tripeptide that declines with age. Promotes collagen synthesis, wound healing, and has broad regenerative effects on skin, hair follicles, and tissues.
Dose: 1-3 mg topical ยท 200-500 mcg injectable | Route: Topical cream/serum or subcutaneous injection
A thymic peptide approved in over 35 countries for immune modulation. Enhances T-cell function, dendritic cell maturation, and anti-viral/anti-tumor immunity without overstimulation.
Dose: 1.6-3.2 mg | Route: Subcutaneous injection
Read full Thymosin Alpha-1 guide →
A D-retro-inverso peptide that disrupts FOXO4-p53 interaction in senescent cells, triggering selective apoptosis of senescent cells while sparing healthy cells.
Dose: 5-10 mg/kg (animal studies) | Route: Subcutaneous
A mitochondria-derived peptide that acts as an exercise mimetic, improving metabolic homeostasis, insulin sensitivity, and fat oxidation. Levels decline significantly with age.
Dose: 5-10 mg | Route: Subcutaneous injection
A family of small peptides complexed with copper ions that stimulate collagen synthesis, wound healing, and skin remodeling. Beyond GHK-Cu, includes AHK-Cu and other tripeptide-copper complexes.
Dose: 1-3% topical solution | Route: Topical
Read full Copper Peptides guide →
A lipopeptide of palmitic acid linked to pentapeptide KTTKS. One of the most researched anti-aging cosmeceutical peptides, stimulating collagen and fibronectin.
Dose: 2-8% in serum/cream | Route: Topical
A synthetic hexapeptide that mimics SNAP-25 protein. Often called "topical Botox," it reduces expression lines by inhibiting neurotransmitter release at neuromuscular junctions.
Dose: 5-10% solution | Route: Topical
A pentapeptide mimicking enkephalin that binds enkephalin receptors on nerve cells, reducing neural excitability and complementing argireline for enhanced anti-wrinkle effects.
Dose: 3-5% solution | Route: Topical
An elongated version of argireline (8 vs 6 amino acids) providing enhanced SNARE complex inhibition for superior wrinkle reduction.
Dose: 3-10% solution | Route: Topical
A lipopeptide acting as a matrikine, signaling skin repair by mimicking collagen breakdown products that trigger fibroblast collagen production.
Dose: 2-5% in formulation | Route: Topical
Read full Palmitoyl Tripeptide-1 guide →
A lipopeptide that reduces IL-6 secretion and inflammaging. Often paired with Pal-Tripeptide-1 as "Matrixyl 3000" for combined collagen-building and anti-inflammatory action.
Dose: 2-4% in formulation | Route: Topical
Read full Palmitoyl Tetrapeptide-7 guide →
The advanced acetylated formulation of argireline with improved delivery and stability for topical anti-wrinkle applications.
Dose: 5-10% | Route: Topical
Read full Acetyl Hexapeptide-8 guide →