Research compounds and peptides that improve sleep quality and recovery - DSIP, melatonin peptides, and relaxation compounds.
A nonapeptide discovered in 1977 that modulates sleep architecture by promoting delta wave (deep sleep) patterns and normalizing circadian disruptions.
Dose: 100-300 mcg | Route: Subcutaneous injection
A synthetic analog of tuftsin with Pro-Gly-Pro for stability. Developed at the Russian Academy of Sciences with anxiolytic and nootropic properties without sedation or addiction.
Dose: 250-750 mcg per spray dose | Route: Intranasal spray
A synthetic peptide from ACTH(4-10) with Pro-Gly-Pro stabilization. Approved in Russia for stroke and cognitive disorders. Enhances attention, memory, and neuroplasticity.
Dose: 200-600 mcg per dose | Route: Intranasal drops/spray
A synthetic hexapeptide and one of the most potent GHRPs. Produces strong GH release but also modestly increases cortisol and prolactin.
Dose: 100-300 mcg | Route: Subcutaneous
An experimental peptide analog enhancing GABAergic sleep signaling without benzodiazepine-like tolerance and dependence. Selectively targets sleep-active VLPO neurons.
Dose: 200-500 mcg | Route: Subcutaneous
A highly bioavailable magnesium form developed to cross the blood-brain barrier and raise brain magnesium levels. Biohackers use it for sleep quality, cognition, and stress, distinct from magnesium fo
Dose: ~1.5-2 g compound (~144 mg elemental Mg) | Route: Oral (capsule or powder)
Read full Magnesium L-Threonate guide →
A flavone found in chamomile and parsley, popularized by longevity researchers as part of an evening sleep stack. Biohackers use it for sleep onset, relaxation, and its NAD-preserving and anti-inflamm
Dose: 50 mg per day | Route: Oral capsule
The primary hormone that signals darkness and regulates the sleep-wake cycle. Beyond sleep onset, biohackers use it for circadian alignment, jet lag, and its potent antioxidant and mitochondrial-prote
Dose: 0.3-5 mg before bed | Route: Oral or sublingual